New Drug Discovery in Hematology
Advancing novel therapeutic agents for the treatment of malignancy into the marketplace is an increasingly costly and lengthy process. As such, new strategies for drug discovery are needed. Drug repurposing represents an opportunity to rapidly advance new therapeutic strategies into clinical trials at a relatively low cost. Known on-patent or off-patent drugs with unrecognized anticancer activity can be rapidly advanced into clinical testing for this new indication by leveraging their known pharmacology, pharmacokinetics, and toxicology. Using this approach, academic groups can participate in the drug discovery field and smaller biotechnology companies can “de-risk” early-stage drug discovery projects. Here, several scientific approaches used to identify drug repurposing opportunities are highlighted, with a focus on hematologic malignancies. In addition, a discussion of the regulatory issues that are unique to drug repurposing and how they impact developing old drugs for new indications is included. Finally, the mechanisms to enhance drug repurposing through increased collaborations between academia, industry, and non-profit charitable organizations are discussed.
· Hematopoietic Cells Mobilization
· Patient-reported outcomes in drug development
· De novo drug discovery
· Drug Repurposing
· Clinical trials
· Future directions and conclusions
Related Conference of New Drug Discovery in Hematology
New Drug Discovery in Hematology Conference Speakers
Recommended Sessions
- Biomarkers in Hematology.
- Blood based products.
- Blood Disorders Diagnosis and treatment.
- Blood Transfusion
- Genetic Blood Disorders
- Hemato-Oncology
- Hematology
- Hematology & Neurological disorders
- Hematology Nursing
- Hematopathology
- Hemochromatosis
- Immunohematology
- New Drug Discovery in Hematology
- Pediatric Hematology
- Polymerase chain reaction in hematological malignancies.
- Stem Cell Research
- Thalassemia
- Vascular Disorders & Hematology
- Veterinary Hematology
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