23^rd World Hematology Congress

Genetic Blood Disorders

Genetic Blood disorder is a state where problem is with blood cells and blood components like white blood cells (WBC), circulating platelets and red blood cells (RBC). Any depletion or damaged platelets cause abnormalities in clot formation. Whereas these red blood cells carry oxygen to tissues play a vital role in organ survival decreased oxygen carrying capacity of RBC leads to some disorders like fatigue, shortness of breath, auto immune haemolytic anaemia and also lack of oxygenated blood to brain. Bone marrow dysfunction is the main cause for low levels of white blood cells in some cases WBC gets destroyed by auto immune disorders there by leading to decreased levels and increasing the sort of infections attack.

Depleted levels of leukocytes is a sign that immune system is not having the capacity to handle infections, chronic inflammation utilises leukocytes faster than they are produced leading to dysfunction of bone marrow ultimately triggering the low levels of WBC.

• Lymphoma.
• Myelodysplastic syndrome.
• Von Willebrand disease.
• Plasma cell myeloma.
• Primary thrombocythemia.
• Haemophilia
• Sickle Cell Anemia
• Thalassemia
• Thrombocytopenia
• Fibrinolytic Disorder
• Congenital Neutropenia